Revolutionizing IBD Management
Continuous, Non-Invasive Inflammation Monitoring for Crohn's Disease & Ulcerative Colitis
Real-time tracking of CRP and Calprotectin through innovative passive-sweat sensor technology. Monitor your biomarkers 24/7 to detect inflammation activity.
Caution: INVESTIGATIONAL DEVICE. LIMITED BY FEDERAL (OR U.S.) LAW TO INVESTIGATIONAL USE ONLY
IBD AWARE ® is currently limited to investigational use within approved clinical research studies and is not available for patient purchase or clinical use outside the approved clinical studies.
A Groundbreaking Solution for IBD Patients
IBD AWARE® represents a paradigm shift in inflammatory bowel disease management. For the first time, patients and clinicians can access continuous, real-time monitoring of critical inflammation biomarkers without invasive blood draws or uncomfortable stool sampling.
IBD AWARE® provides unprecedented insights into disease activity, treatment effectiveness, and impending flares. Developed in collaboration with leading IBD clinicians and funded by the Crohn's & Colitis Foundation and ARPA-H, IBD AWARE® is under investigation as a potential remote monitoring decision-support device for enabling proactive disease management.
Clinical-Grade Monitoring
Clinical data in several peer-reviewed studies with our partners and Crohn's & Colitis Foundation. Correlation established with serum and stool biomarkers.
Passive Sweat Sensing
No blood draws, No stool samples, No exercise required. Our sensors analyze natural occurring perspiration for continuous, effortless tracking using our easy-to-use device.
Treatment Optimization
Track how medications impact inflammation in real-time, in consultation with your IBD clinician towards proactive disease management.
24/7 Inflammation Tracking
Track your inflammation levels and monitor your disease activity. Share data seamlessly with your healthcare team for informed decision-making and remote monitoring.
IBD AWARE® IMPACT
500K+
Perspiration biomarker readings collected
24/7
Continuous Inflammation tracking established
85%+
Accuracy in clinical studies on inflamed vs. healthy states
4
Biomarkers per sensor tracked simultaneously
Calprotectin
Gold standard for gut inflammation. Correlates with fecal calprotectin but measured continuously in sweat.
C-Reactive Protein
(CRP)
Systemic inflammation biomarker. Elevated CRP signals active disease and response to treatment.
Tumor Necrosis Factor-Alpha (TNF-α)
Key inflammatory cytokine targeted by many biologic therapies. Monitor treatment effectiveness in real-time.
Interleukin-6
(IL-6)
Inflammatory marker linked to disease activity and severity. Early indicator of inflammation.
How IBD AWARE® Works
1
Wear Comfortably
Apply the IBD AWARE sensor to your skin. It's lightweight, flexible, and designed for comfortable 24/7 wear.
2
Passive Sampling
The sensor continuously analyzes naturally occurring perspiration—no active sweating or exercise needed.
3
Continuous Tracking
Proprietary sweat sensor technology measures systemic inflammation throughout your day and night.
4
Real-Time Insights
View your biomarker patterns on SWEAT AWARE app for personalized insights of inflammation activity.
IBD AWARE® Benefits
For Patients
Proactive IBD Management
Detect inflammation changes over the course of the day and monitor in real-time, allowing early intervention.
Lifestyle Insights
Understand how diet, stress, sleep, and activities affect your inflammation levels in real-time.
Stay in Remission
Maintain remission by monitoring inflammation and managing disease activity before they become flares.
Reduce Testing Burden
Minimize frequent blood/stool testing and schedule colonoscopy based on need and IBD AWARE alerts.
For Clinicians
Comprehensive Disease View
Access continuous biomarker trends rather than single-point-in-time measurements during office visits.
Treatment Optimization
Assess biologic therapy effectiveness in real-time and adjust dosing or switch treatments with confidence.
Remote Patient Monitoring
Track patients between visits, identify patterns with flare risk, and provide timely interventions.
Real-time Biomarker data
Make treatment decisions based on real-time biomarker data rather than patient-reported symptoms alone.
Medical Device Information
Current Status: IBD AWARE® is an investigational device which is limited by federal (or U.S.) law to investigational use only and available for research use and under approved IRB monitored clinical studies.
Regulatory Path: IBD AWARE® is anticipated to undergo FDA regulatory submission as a medical device prescribed by clinicians.
Prescription-Based: Upon FDA clearance, IBD AWARE® will be prescribed to you by your gastroenterologist based on your disease state and monitoring needs.